Appearance: White Fine Powder
Tranexamic acid is a synthetic derivative of the amino acid lysine.Tranexamic acid (commonly marketed in tablet form as Lysteda and in IV form as Cyklokapron in the U.S.and as Transamin,Transcam in Asia, and Espercil in South America) is often prescribed for excessive bleeding.
acid is an anti-fibrinolytic that competitively inhibits the activation
of plasminogen to plasmin, a molecule responsible for the degradation of
fibrin. Fibrin is the basic framework for the formation of a blood clot
in hemostasis.It has roughly 8 times the anti-fibrinolytic
activity of an older analogue, ε-aminocaproic acid.
≤ 10.0 mg/kg
≤ 2.0 mg/kg
≤ 1.0 mg/kg
Function & Application:
Tranexamic Acid 99% Powder for Skin exerts its anti fibrinolytic effect through the reversible blockade of lysine binding sites on plasminogen molecules. It inhibits endometrial plasminogen activator and thus prevents fibrinolysis and the breakdown of blood clots.
It is used as firstline nonhormonal treatment of dysfunctional uterine bleeding,and heavy bleeding associated with uterine fibroids.
It is used in orthopedic surgery to reduce bloodloss. It is of proven value in clearing the field of surgery and reducing pre- and postoperative blood loss. Drain and number of transfusions are reduced. It is commonly used in joint replacement surgery.
It should be considered for use in bleeding trauma patients.
Tranexamic Acid 99% Powder for Skin is used in dentistry in the form of a 5% mouth rinse after extractions or surgery in patients with prolonged bleeding time, e.g. from acquired or inherited disorders.
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